Visiting from out of town and everyone was so helpful and kind. They transferred my prescription no problem. It was ready quickly and for a great price! Highly recommend.Patient Review
Welcome to Twain Harte Pharmacy
Care You Can Count On.
Locally owned, community focused, and proud to be one of the county’s two remaining independent pharmacies.
View pharmacy hours belowGet directions (opens in a new tab)Mon–Thu 9:00 AM–5:30 PM · Fri 9:00 AM–6:00 PM · Weekends closed
Your Pharmacy Experts
Proudly voted Best Pharmacy in The Union Democrat Readers’ Choice Awards 2025 — thank you for trusting us to care for our community!
Vaccinations available right here in Twain HarteImmunizations
Protect your health, close to home
Our pharmacists offer routine and seasonal immunizations with the personal attention you expect from your neighborhood pharmacy.
- Flu
- Pneumococcal
- RSV
- Shingles
- Tdap or TD
Walk-ins may be available. Call the pharmacy to schedule an appointment.
Explore immunizationsVisit us
Hours & location
22629 Twain Harte Drive, Suite D, Twain Harte, CA 95383 (opens in a new tab)
| Day | Hours |
|---|---|
| Monday | 9:00 AM – 5:30 PM |
| Tuesday | 9:00 AM – 5:30 PM |
| Wednesday | 9:00 AM – 5:30 PM |
| Thursday | 9:00 AM – 5:30 PM |
| Friday | 9:00 AM – 6:00 PM |
| Saturday | Closed |
| Sunday | Closed |
Closed for lunch Monday–Thursday, 1:00 PM–1:30 PM; Friday, 1:00 PM–2:00 PM.
This quirky, old-school dry goods store has all kinds of gems. Games, puzzles, fabric, crafts, clothing, candy and (of course) a fully-stocked pharmacy. More fun than your average drug store, for sure.Patient Review
It's my go-to place for pretty much everything we need. The staff are friendly and helpful and the Pharmacy delivers.Patient Review
Patient Portal
Your pharmacy, right in your pocket
Request refills, message the pharmacy securely, schedule appointments, and manage medications for your whole family — all from your phone.
